Dosage of Refucil Syrup This is a Prescription-Only Medicine (POM). The dosage is strictly determined by a doctor based on the child’s weight and the location of the infection.

• Standard Pediatric Dose: Usually 10mg to 20mg per kg of body weight per day.
• Duration: Treatment is often long-term because the medicine must wait for new hair or skin to grow.
  • Scalp/Skin: 4 to 6 weeks.
  • Fingernails: 4 months.
  • Toenails: 6 months or more.

Proper Administration

• The "Fatty Meal" Rule: Crucial: Griseofulvin is absorbed much better when taken with a meal containing fat. Give the syrup with whole milk, ice cream, cheese, or a meal cooked with oil/butter.
• Shake Well: Always shake the bottle vigorously before each dose to ensure the medicine is not settled at the bottom.
• Consistency: Give the dose at the same time every day to maintain a steady level in the keratin precursor cells.
• Do Not Stop Early: Even if the skin looks clear, the fungus may still be in the hair follicles or nail beds. Finish the entire course prescribed by the doctor.

How to Store and Dispose of Refucil Syrup

• Storage: Store at room temperature (below 25°C). Keep the bottle tightly closed and protect it from direct light.
• Disposal: Keep out of reach of children. Return unused portions to the pharmacy.

Quick Tips for Refucil Syrup

• Hygiene: Keep your child's towels, hats, and combs separate from others to prevent the spread of the fungus during treatment.
• Sun Protection: Griseofulvin can make the skin more sensitive to sunlight (photosensitivity). Use hats and sunscreen when the child is outdoors.
• Nail Care: Keep infected nails trimmed short to help the medicine work more effectively.

Safety and Precautions

Contraindications of Refucil Syrup

• Pregnancy: Strictly contraindicated. It can cause severe birth defects. Female adolescents must use effective contraception during and for one month after treatment.
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• Liver Disease: Do not use if the patient has liver failure or impaired liver function.
• Porphyria: Do not use, as it can trigger attacks of this genetic blood disorder.
• Lupus: May worsen Systemic Lupus Erythematosus (SLE).

Side Effects of Refucil Syrup

• Common: Headache (usually disappears as treatment continues), nausea, or diarrhea.
• Less Common: Dizziness, fatigue, or white patches in the mouth (thrush).
• Serious: Severe skin rash with peeling, or yellowing of the eyes/skin (jaundice).
• Action: If the child develops a widespread rash or a high fever, stop use and contact your doctor immediately.

Precautions and Warnings

• Penicillin Allergy: Use with caution; some cross-sensitivity may occur since Griseofulvin is derived from Penicillium.

Drug Interactions: Griseofulvin can decrease the effectiveness of blood thinners (Warfarin) and hormonal contraceptives. It also interacts with alcohol (antabuse-like effect).

• Pack Size: 100ml Amber Bottle.
• Manufacturer: Oak-Faith Pharmaceutical / Reals Pharmaceuticals.
• Form: Oral Suspension.
• Active Ingredient: Griseofulvin 125mg per 5ml.