Dosage of Maldox Suspension 15mL

Maldox Suspension 15mL is a Prescription Only Medicine (POM).

Take as directed by the pharmacist or physician.

Dosage, particularly for children and for prophylaxis, is based strictly on body weight and specific medical guidelines. Overdose is especially hazardous.

Proper Administration

• Route: Oral suspension.
• How to Take: Shake the bottle well before use. Measure the prescribed dose carefully using the provided measuring device (e.g., spoon or syringe). It can be taken with or without food.
• Best Time of Day: For malaria prophylaxis, it should be taken on a regular schedule, preferably on the same day each week. For treatment, follow your doctor's exact timing instructions.

Missed Dose Guidance

• If you miss a dose, take it as soon as you remember.
• If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule.
• Do not take a double dose to compensate for a missed dose.

Contraindications of Maldox Suspension 15mL

Do NOT take Maldox Suspension 15mL if you:

• Have a known allergy or hypersensitivity to Sulfadoxine, Pyrimethamine, or other sulfa drugs.
• Have megaloblastic anemia due to folate deficiency.
• Have certain blood cell disorders (blood dyscrasias).
• Have severe liver or kidney failure, particularly if prolonged prophylactic use is intended.
• Are an infant less than 2 months of age.
• Are in the first trimester of pregnancy (due to potential risk to the fetus) or at term (late pregnancy).

Pregnancy & Breastfeeding Warnings

• Pregnancy: Maldox Suspension should be avoided during the first trimester. It is used for intermittent preventive treatment in pregnant women during the second and third trimesters only when the benefit is considered to outweigh the risks, and only under strict medical direction.
• Breastfeeding: Both active ingredients are excreted in human milk. Maldox Suspension is generally compatible with breastfeeding, but it should be avoided in premature infants and in infants with hyperbilirubinemia or glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Side Effects of Maldox Suspension 15mL

This medication can cause serious side effects, which require immediate attention.

• More Common Side Effects (Mild and Expected): Diarrhea, headache, anxiety, drowsiness, nervousness, mild stomach pain, loss of appetite, and dizziness.
• Serious but Rare Side Effects (that may require medical attention):
  • Severe Skin Reactions: The first sign of any skin rash (no matter how mild), severe blistering, peeling, or a red skin rash (may signal life-threatening conditions like Stevens-Johnson syndrome).
  • Blood Disorders: Pale skin, easy bruising or bleeding, fever, chills, sore throat, or unusual tiredness (signs of blood dyscrasias).
  • Liver/Kidney Problems: Jaundice (yellowing of the skin or eyes), dark urine, urinating less than usual, or swelling.
  • Other: Convulsions (seizures), hallucinations, or a swollen tongue.

What to do if side effects occur:

• For common side effects, consult your doctor if they persist or become bothersome.
• For any serious side effect, especially the first sign of any skin rash or sore throat, stop taking Maldox Suspension 15mL immediately and seek emergency medical attention.

Precautions and Warnings of Maldox Suspension 15mL

• Stop Immediately: Discontinue the medication if you notice a skin rash, sores in the mouth, sore throat, or severe bruising, as these can be early signs of serious complications.
• Folate Deficiency: If you have an existing folate deficiency, your doctor must monitor your condition closely.
• G6PD Deficiency: Use with caution if you have Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency, as there is a risk of hemolytic anemia.
• Sun Sensitivity: Maldox Suspension 15mL can make your skin more sensitive to sunlight. Avoid direct sunlight, sunlamps, or tanning beds while taking this medication. Wear protective clothing and use sunscreens.
• Drug Interactions: Avoid concomitant use with Trimethoprim, Sulfamethoxazole/Trimethoprim, or any other sulfonamide, as this can severely increase the risk of adverse hematological (blood) and cutaneous (skin) reactions.

The active ingredients in this oral suspension are Sulfadoxine and Pyrimethamine. It is supplied in a 15mL bottle. It is a Prescription Only Medicine (POM). The concentration is typically 500 mg Sulfadoxine and 25 mg Pyrimethamine per 5 mL of suspension.