Dosage of Sirdalud This is a Prescription-Only Medicine (POM). Take exactly as directed by your physician. Dosage must be individualized to find the balance between relief and side effects (like drowsiness).

• For Painful Spasms: The usual dose is 2mg to 4mg taken three times daily.
• For Spasticity: The starting dose is usually 2mg daily, gradually increased by 2mg increments at weekly intervals until the desired effect is reached.

Proper Administration

• Method: Swallow the tablet whole with a glass of water.
• Consistency: Sirdalud can be taken with or without food, but you should choose one way and be consistent, as food can change how much medicine your body absorbs.
• Timing: If you experience significant drowsiness, your doctor may suggest taking the largest portion of your daily dose at bedtime.
• Missed Dose: Take it as soon as you remember. If it is almost time for your next dose, skip the missed one. Never double the dose.

How to Store and Dispose of Sirdalud

• Storage: Store in the original package in a cool, dry place below 30°C.
• Disposal: Keep out of reach of children. Return unused or expired medication to a pharmacy for safe disposal.

Quick Tips for Sirdalud

• Do Not Stop Abruptly: If you have been taking Sirdalud at high doses for a long time, stopping suddenly can cause a rapid heartbeat and high blood pressure. Always taper the dose under medical supervision.
• Drowsiness Warning: This medication often causes significant sleepiness. Avoid driving or operating machinery until you are certain of your reaction.
• Avoid Alcohol: Alcohol can dangerously increase the sedative effects of Sirdalud and should be avoided.

Safety and Precautions

Contraindications of Sirdalud

• Liver Function: Do NOT use if you have severely impaired liver function.
• Drug Interactions: Do NOT take Sirdalud if you are taking potent inhibitors of CYP1A2, such as Fluvoxamine or Ciprofloxacin (an antibiotic). Combining these can lead to dangerously high levels of Tizanidine.
• Allergies: Avoid if you have a known hypersensitivity to Tizanidine.

Side Effects of Sirdalud

• Common: Drowsiness, fatigue, dizziness, dry mouth, and a slight decrease in blood pressure.
• Rare: Nausea, stomach upset, or a transient rise in liver enzymes.
• Action: If you experience severe weakness, fainting, or yellowing of the skin/eyes (jaundice), stop use and see a doctor immediately.

Precautions and Warnings

• Blood Pressure: It may cause low blood pressure (hypotension). Be careful when standing up quickly from a sitting or lying position.
• Kidney Health: Patients with renal impairment may require a lower starting dose and frequent monitoring.
• Pregnancy & Breastfeeding: Not recommended unless the benefit clearly outweighs the risk. Consult your healthcare provider.

• Pack Size: Usually 30 tablets per pack.
• Form: Oral Tablet (available in 2mg and 4mg strengths).
• Active Ingredient: Tizanidine.