Dosage/Direction for Use
The usual course of therapy is seven days (range 5 to 10 days).
Tablet: ZINNAT should be taken after food for optimum absorption.

• Adults: Tablet: Most infections: 250 mg twice daily.
• Urinary tract infections: 250 mg twice daily.
• Mild to moderate lower respiratory tract infections e.g. bronchitis: 250 mg twice daily.
• More severe lower respiratory tract infections, or if pneumonia is suspected: 500 mg twice daily.
• Pyelonephritis: 250 mg twice daily.
• Uncomplicated gonorrhoea: Single dose of 1 g.
• Sequential therapy: Pneumonia: 1.5 g ZINACEF twice daily (given i.v. or i.m.) for 48 to 72 hours, followed by 500 mg twice daily ZINNAT (cefuroxime axetil) oral therapy for 7 to 10 days.
• Acute exacerbations of chronic bronchitis: 750 mg ZINACEF twice daily (given i.v. or i.m.) for 48 to 72 hours, followed by 500 mg twice daily ZINNAT (cefuroxime axetil) oral therapy for 5 to 10 days. Duration of parenteral  is determined by the severity of the infection and the clinical status of the patient.

ZINNAT tablets should not be crushed or split and are therefore unsuitable for treatment of patients, such as younger children, who cannot swallow whole tablets.
There is no experience of using ZINNAT in children under the age of 3 months.
 

Indications include: Upper respiratory tract infections for example, ear, nose and throat infections, such as otitis media, sinusitis, tonsillitis and pharyngitis; lower respiratory tract infections for example, pneumonia, acute bronchitis, and acute exacerbations of chronic bronchitis; genito-urinary tract infections for example, pyelonephritis, cystitis and urethritis; skin and soft tissue infections for example, furunculosis, pyoderma and impetigo; gonorrhoea, acute uncomplicated gonococcal urethritis, and cervicitis.