Oxyurea 500mg
Oxyurea 500mg
Oxyurea 500mg Is A Potent Antineoplastic (anti-cancer) And Hematological Agent Containing Hydroxyurea. It Is A Versatile Medication Used Primarily To Manage Certain Types Of Blood ...
Oxyurea 500mg Is A Potent Antineoplastic (anti-cancer) And Hematological Agent Containing Hydroxyurea. It Is A Versatile Medication Used Primarily To ...
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About this item
Oxyurea works as a cytotoxic agent that specifically targets cells during the DNA synthesis phase of their cycle. In cancer treatment, it slows the growth of malignant cells. In Sickle Cell Disease, it works through a unique mechanism: it stimulates the body to produce Fetal Hemoglobin (HbF). Since HbF does not "sickle," having more of it prevents red blood cells from deforming, which keeps blood vessels clear and reduces pain and organ damage.
Dosage of Oxyurea 500mg This is a Prescription-Only Medicine (POM) and must be monitored by a specialist (Hematologist or Oncologist).
- Sickle Cell Disease: Usually starts at 15mg/kg once daily, with the dose adjusted based on blood counts.
- CML/Polycythemia: Dosage varies widely based on the patient's body weight and blood response.
- Blood Tests: You will require frequent blood tests (Complete Blood Count) to ensure the dose is safe and effective.
Proper Administration
- Method: Swallow the capsule whole with a glass of water. Do not open, crush, or chew the capsules.
- Handling: Because this is a cytotoxic drug, caregivers should wear disposable gloves when handling the capsules or wash their hands thoroughly before and after touching the bottle.
- Timing: Take it at the same time every day. It can be taken with or without food.
- Hydration: Drink plenty of fluids (8–10 glasses of water daily) unless otherwise directed, to help your kidneys flush the medication.
How to Store and Dispose of Oxyurea 500mg
- Storage: Store in a cool, dry place below 25°C. Keep the bottle tightly closed.
- Disposal: Do not throw this medication in household trash or down the drain. Return any unused capsules to a hospital or pharmacy that handles hazardous medical waste.
Quick Tips for Oxyurea 500mg
- Folic Acid: Your doctor will often prescribe Folic Acid alongside Oxyurea to support healthy red blood cell production.
- Sun Protection: This medication can make your skin more sensitive to the sun and increase the risk of skin cancer. Use sunscreen and wear protective clothing.
- Contraception: Both men and women should use effective birth control while taking Oxyurea and for several months after stopping, as it can cause birth defects.
Safety and Precautions
Contraindications of Oxyurea 500mg
- Severe Bone Marrow Suppression: Do not use if white blood cell or platelet counts are dangerously low.
- Pregnancy & Breastfeeding: Strictly contraindicated. It can cause fetal harm. Breastfeeding should be discontinued during treatment.
- Hypersensitivity: Do not use if you are allergic to Hydroxyurea or any of its components.
Side Effects of Oxyurea 500mg
- Common: Mild nausea, loss of appetite, thinning hair, or darkening of the skin/nails.
- Serious: Fever, chills, or signs of infection (due to low white blood cells); unusual bruising or bleeding; or painful mouth ulcers.
- Action: If you develop a high fever, severe skin ulcers, or shortness of breath, contact your specialist immediately.
Precautions and Warnings
- Infections: Stay away from people who are sick, as your immune system may be weakened.
- Vaccinations: Avoid "live" vaccines (like the yellow fever or oral polio vaccine) while taking this medication.
- Liver & Kidney Function: Dosage adjustments are necessary for patients with impaired kidney or liver function.
- Pack Size: Usually 100 capsules per bottle.
- Form: Oral Capsule.
- Active Ingredient: Hydroxyurea 500mg.
About this item
Oxyurea works as a cytotoxic agent that specifically targets cells during the DNA synthesis phase of their cycle. In cancer treatment, it slows the growth of malignant cells. In Sickle Cell Disease, it works through a unique mechanism: it stimulates the body to produce Fetal Hemoglobin (HbF). Since HbF does not "sickle," having more of it prevents red blood cells from deforming, which keeps blood vessels clear and reduces pain and organ damage.
Dosage of Oxyurea 500mg This is a Prescription-Only Medicine (POM) and must be monitored by a specialist (Hematologist or Oncologist).
- Sickle Cell Disease: Usually starts at 15mg/kg once daily, with the dose adjusted based on blood counts.
- CML/Polycythemia: Dosage varies widely based on the patient's body weight and blood response.
- Blood Tests: You will require frequent blood tests (Complete Blood Count) to ensure the dose is safe and effective.
Proper Administration
- Method: Swallow the capsule whole with a glass of water. Do not open, crush, or chew the capsules.
- Handling: Because this is a cytotoxic drug, caregivers should wear disposable gloves when handling the capsules or wash their hands thoroughly before and after touching the bottle.
- Timing: Take it at the same time every day. It can be taken with or without food.
- Hydration: Drink plenty of fluids (8–10 glasses of water daily) unless otherwise directed, to help your kidneys flush the medication.
How to Store and Dispose of Oxyurea 500mg
- Storage: Store in a cool, dry place below 25°C. Keep the bottle tightly closed.
- Disposal: Do not throw this medication in household trash or down the drain. Return any unused capsules to a hospital or pharmacy that handles hazardous medical waste.
Quick Tips for Oxyurea 500mg
- Folic Acid: Your doctor will often prescribe Folic Acid alongside Oxyurea to support healthy red blood cell production.
- Sun Protection: This medication can make your skin more sensitive to the sun and increase the risk of skin cancer. Use sunscreen and wear protective clothing.
- Contraception: Both men and women should use effective birth control while taking Oxyurea and for several months after stopping, as it can cause birth defects.
Safety and Precautions
Contraindications of Oxyurea 500mg
- Severe Bone Marrow Suppression: Do not use if white blood cell or platelet counts are dangerously low.
- Pregnancy & Breastfeeding: Strictly contraindicated. It can cause fetal harm. Breastfeeding should be discontinued during treatment.
- Hypersensitivity: Do not use if you are allergic to Hydroxyurea or any of its components.
Side Effects of Oxyurea 500mg
- Common: Mild nausea, loss of appetite, thinning hair, or darkening of the skin/nails.
- Serious: Fever, chills, or signs of infection (due to low white blood cells); unusual bruising or bleeding; or painful mouth ulcers.
- Action: If you develop a high fever, severe skin ulcers, or shortness of breath, contact your specialist immediately.
Precautions and Warnings
- Infections: Stay away from people who are sick, as your immune system may be weakened.
- Vaccinations: Avoid "live" vaccines (like the yellow fever or oral polio vaccine) while taking this medication.
- Liver & Kidney Function: Dosage adjustments are necessary for patients with impaired kidney or liver function.
- Pack Size: Usually 100 capsules per bottle.
- Form: Oral Capsule.
- Active Ingredient: Hydroxyurea 500mg.
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